diff --git a/ddtrace/internal/settings/_otel_remapper.py b/ddtrace/internal/settings/_otel_remapper.py
index d5ccce52528..93e6d6e436e 100644
--- a/ddtrace/internal/settings/_otel_remapper.py
+++ b/ddtrace/internal/settings/_otel_remapper.py
@@ -133,6 +133,8 @@ def _remap_default(otel_value: str) -> Optional[str]:
 # https://github.com/open-telemetry/opentelemetry-python/blob/v1.34.1/opentelemetry-sdk/src/opentelemetry/sdk/environment_variables/__init__.py
 SUPPORTED_OTEL_ENV_VARS = {
     "OTEL_PYTHON_CONTEXT",
+    "OTEL_METRIC_EXPORT_INTERVAL",
+    "OTEL_METRIC_EXPORT_TIMEOUT",
     "OTEL_TRACES_SAMPLER_ARG",
     "OTEL_EXPORTER_OTLP_TIMEOUT",
     "OTEL_EXPORTER_OTLP_PROTOCOL",
@@ -158,6 +160,7 @@ def _remap_default(otel_value: str) -> Optional[str]:
     "OTEL_EXPORTER_OTLP_METRICS_INSECURE",
     "OTEL_EXPORTER_OTLP_METRICS_COMPRESSION",
     "OTEL_EXPORTER_OTLP_METRICS_TIMEOUT",
+    "OTEL_EXPORTER_OTLP_METRICS_TEMPORALITY_PREFERENCE",
     "OTEL_EXPORTER_OTLP_TRACES_PROTOCOL",
     "OTEL_EXPORTER_OTLP_TRACES_ENDPOINT",
     "OTEL_EXPORTER_OTLP_TRACES_CERTIFICATE",
diff --git a/releasenotes/notes/add-otel-configs-to-allowlist-bcf2be5c9ed79b61.yaml b/releasenotes/notes/add-otel-configs-to-allowlist-bcf2be5c9ed79b61.yaml
new file mode 100644
index 00000000000..00e09d00192
--- /dev/null
+++ b/releasenotes/notes/add-otel-configs-to-allowlist-bcf2be5c9ed79b61.yaml
@@ -0,0 +1,5 @@
+---
+other:
+  - |
+    opentelemetry: Adds ``OTEL_METRIC_EXPORT_TIMEOUT`` and ``OTEL_EXPORTER_OTLP_METRICS_TEMPORALITY_PREFERENCE`` to the allowlist of recognized OpenTelemetry environment variables.
+    Previously, setting any of these variables produced an inaccurate ``OpenTelemetry configuration ... is not supported by Datadog`` warning at startup, even though the variables are valid OpenTelemetry SDK settings.