diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 4b7fed5..c9ab595 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -27,7 +27,7 @@ jobs:
       - name: Install dependencies
         run: |
           python -m pip install --upgrade pip
-          pip install ruff pytest pytest-cov 
+          pip install ruff pytest pytest-cov click
           pip install -e . -e test/juliapkg_test_editable_setuptools
       - name: Lint with ruff
         run: |
diff --git a/CHANGELOG.md b/CHANGELOG.md
index fc094c1..0ba99f0 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,6 +1,7 @@
 # Changelog
 
 ## Unreleased
+* Add the CLI.
 * Improve some error messages.
 
 ## v0.1.18 (2025-09-01)
diff --git a/README.md b/README.md
index 3efc8c1..4d281aa 100644
--- a/README.md
+++ b/README.md
@@ -55,6 +55,18 @@ Julia v1.*.* and the Example package v0.5.*:
 }
 ```
 
+### Command line interface
+
+You can also use the CLI, some examples:
+```sh
+python -m juliapkg --help
+python -m juliapkg add Example --uuid=7876af07-990d-54b4-ab0e-23690620f79a --version=0.5
+python -m juliapkg resolve
+python -m juliapkg status
+python -m juliapkg run -E 'using Example; Example.hello("world")'
+python -m juliapkg remove Example
+```
+
 ## Using Julia
 
 - `juliapkg.executable()` returns a compatible Julia executable.
diff --git a/pyproject.toml b/pyproject.toml
index 03511ee..f62fde6 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -11,6 +11,9 @@ classifiers = [
     "Programming Language :: Python :: 3",
 ]
 
+[project.optional-dependencies]
+cli = ["click >=8.0,<9.0"]
+
 [project.urls]
 Homepage = "http://github.com/JuliaPy/pyjuliapkg"
 Repository = "http://github.com/JuliaPy/pyjuliapkg.git"
diff --git a/src/juliapkg/__main__.py b/src/juliapkg/__main__.py
new file mode 100644
index 0000000..1490994
--- /dev/null
+++ b/src/juliapkg/__main__.py
@@ -0,0 +1,6 @@
+"""Entry point for python -m juliapkg."""
+
+if __name__ == "__main__":
+    from .cli import cli
+
+    cli()
diff --git a/src/juliapkg/cli.py b/src/juliapkg/cli.py
new file mode 100644
index 0000000..6c62bb6
--- /dev/null
+++ b/src/juliapkg/cli.py
@@ -0,0 +1,142 @@
+"""Command-line interface for juliapkg."""
+
+import os
+import subprocess
+import sys
+
+from .deps import STATE, add, resolve, rm, status, update
+
+try:
+    import click
+except ImportError:
+    click = None
+
+if click is None:
+
+    def cli():
+        raise ImportError(
+            "`click` is required to use the juliapkg CLI. "
+            "Please install it with `pip install click` or "
+            '`pip install "pyjuliapkg[cli]".'
+        )
+
+else:
+
+    class JuliaPkgGroup(click.Group):
+        """Custom group to avoid long stacktraces when Julia exits with an error."""
+
+        @property
+        def always_show_python_error(self) -> bool:
+            return (
+                os.environ.get("PYTHON_JULIAPKG_CLI_ALWAYS_SHOW_PYTHON_ERROR", "0")
+                == "1"
+            )
+
+        @staticmethod
+        def _is_graceful_exit(e: subprocess.CalledProcessError) -> bool:
+            """Try to guess if a CalledProcessError was Julia gracefully exiting."""
+            return e.returncode == 1
+
+        def invoke(self, ctx):
+            try:
+                return super().invoke(ctx)
+            except subprocess.CalledProcessError as e:
+                # Julia already printed an error message
+                if (
+                    JuliaPkgGroup._is_graceful_exit(e)
+                    and not self.always_show_python_error
+                ):
+                    click.get_current_context().exit(1)
+                else:
+                    raise
+
+    cli = JuliaPkgGroup(help="JuliaPkg - Manage your Julia dependencies from Python.")
+
+    @cli.command(name="add")
+    @click.argument("package")
+    @click.option("--uuid", required=True, help="UUID of the package")
+    @click.option("--version", help="Version constraint")
+    @click.option("--dev", is_flag=True, help="Add as development dependency")
+    @click.option("--path", help="Local path to package")
+    @click.option("--subdir", help="Subdirectory within the package")
+    @click.option("--url", help="Git URL for the package")
+    @click.option("--rev", help="Git revision/branch/tag")
+    @click.option("--target", help="Target environment")
+    def add_cli(package, uuid, version, dev, path, subdir, url, rev, target):
+        """Add a Julia package to the project."""
+        add(
+            package,
+            uuid=uuid,
+            version=version,
+            dev=dev,
+            path=path,
+            subdir=subdir,
+            url=url,
+            rev=rev,
+            target=target,
+        )
+        click.echo(f"Queued addition of {package}. Run `resolve` to apply changes.")
+
+    @cli.command(name="resolve")
+    @click.option("--force", is_flag=True, help="Force resolution")
+    @click.option("--dry-run", is_flag=True, help="Dry run (don't actually install)")
+    @click.option("--update", is_flag=True, help="Update dependencies")
+    def resolve_cli(force, dry_run, update):
+        """Resolve and install Julia dependencies."""
+        resolve(force=force, dry_run=dry_run, update=update)
+        click.echo("Resolved dependencies.")
+
+    @cli.command(name="remove")
+    @click.argument("package")
+    @click.option("--target", help="Target environment")
+    def remove_cli(package, target):
+        """Remove a Julia package from the project."""
+        rm(package, target=target)
+        click.echo(f"Queued removal of {package}. Run `resolve` to apply changes.")
+
+    @cli.command(name="status")
+    @click.option("--target", help="Target environment")
+    def status_cli(target):
+        """Show the status of Julia packages in the project."""
+        status(target=target)
+
+    @cli.command(name="update")
+    @click.option("--dry-run", is_flag=True, help="Dry run (don't actually install)")
+    def update_cli(dry_run):
+        """Update Julia packages in the project."""
+        update(dry_run=dry_run)
+
+    @cli.command(name="run", context_settings=dict(ignore_unknown_options=True))
+    @click.argument("args", nargs=-1)
+    def run_cli(args):
+        """Pass-through to Julia CLI.
+
+        For example, use `run` to launch a REPL or `run script.jl` to run a script.
+        """
+        resolve()
+        executable = STATE["executable"]
+        project = STATE["project"]
+
+        env = os.environ.copy()
+        if sys.executable:
+            # prefer PythonCall to use the current Python executable
+            # TODO: this is a hack, it would be better for PythonCall to detect that
+            #   Julia is being called from Python
+            env.setdefault("JULIA_PYTHONCALL_EXE", sys.executable)
+        cmd = [
+            executable,
+            "--project=" + project,
+        ]
+        for arg in args:
+            if arg.startswith("--project"):
+                raise ValueError("Do not specify --project when using pyjuliapkg.")
+            cmd.append(arg)
+        subprocess.run(
+            cmd,
+            check=True,
+            env=env,
+        )
+
+
+if __name__ == "__main__":
+    cli()
diff --git a/test/test_cli.py b/test/test_cli.py
new file mode 100644
index 0000000..cc1189c
--- /dev/null
+++ b/test/test_cli.py
@@ -0,0 +1,68 @@
+import importlib
+import sys
+from unittest.mock import patch
+
+import pytest
+
+from juliapkg.cli import cli
+
+
+@pytest.fixture
+def runner():
+    try:
+        from click.testing import CliRunner
+
+        return CliRunner()
+    except ImportError:
+        pytest.skip("click is not available")
+
+
+class TestCLI:
+    def test_cli_help(self, runner):
+        result = runner.invoke(cli, ["--help"])
+        assert result.exit_code == 0
+        assert "JuliaPkg - Manage your Julia dependencies from Python." in result.output
+
+    def test_cli_no_args(self, runner):
+        result = runner.invoke(cli, [])
+        assert "Usage:" in result.output
+
+    def test_run_with_project(self, runner):
+        result = runner.invoke(cli, ["run", "--project=/tmp/test"])
+        assert result.exit_code != 0
+        assert "Do not specify --project when using pyjuliapkg" in str(result.exception)
+
+    def test_run_command(self, runner):
+        result = runner.invoke(cli, ["run", "-e", "using Pkg; Pkg.status()"])
+        assert result.exit_code == 0
+
+    def test_basic_usage(self, runner):
+        result = runner.invoke(
+            cli, ["add", "Example", "--uuid", "7876af07-990d-54b4-ab0e-23690620f79a"]
+        )
+        assert result.exit_code == 0
+        assert "Queued addition of Example" in result.output
+
+        result = runner.invoke(cli, ["resolve"])
+        assert result.exit_code == 0
+
+        result = runner.invoke(cli, ["status"])
+        assert result.exit_code == 0
+        assert "Example" in result.output
+
+        result = runner.invoke(cli, ["remove", "Example"])
+        assert result.exit_code == 0
+        assert "Queued removal of Example" in result.output
+
+        result = runner.invoke(cli, ["resolve", "--force"])
+        assert result.exit_code == 0
+
+    def test_click_not_available(self):
+        with patch.dict(sys.modules, {"click": None, "juliapkg.cli": None}):
+            del sys.modules["juliapkg.cli"]
+            cli_module = importlib.import_module("juliapkg.cli")
+
+            with pytest.raises(ImportError) as exc_info:
+                cli_module.cli()
+
+            assert "`click` is required to use the juliapkg CLI" in str(exc_info.value)