diff --git a/packages/main/src/ListItemCustom.ts b/packages/main/src/ListItemCustom.ts
index 55a3d929ce60..a10d965fdbc1 100644
--- a/packages/main/src/ListItemCustom.ts
+++ b/packages/main/src/ListItemCustom.ts
@@ -1,10 +1,19 @@
 import { isTabNext, isTabPrevious, isF2 } from "@ui5/webcomponents-base/dist/Keys.js";
 import jsxRenderer from "@ui5/webcomponents-base/dist/renderer/JsxRenderer.js";
-import type { ClassMap } from "@ui5/webcomponents-base/dist/types.js";
+import type I18nBundle from "@ui5/webcomponents-base/dist/i18nBundle.js";
+import type { ClassMap, AccessibilityInfo } from "@ui5/webcomponents-base/dist/types.js";
+import slot from "@ui5/webcomponents-base/dist/decorators/slot.js";
 import customElement from "@ui5/webcomponents-base/dist/decorators/customElement.js";
 import property from "@ui5/webcomponents-base/dist/decorators/property.js";
+import i18n from "@ui5/webcomponents-base/dist/decorators/i18n.js";
 import ListItem from "./ListItem.js";
 import ListItemCustomTemplate from "./ListItemCustomTemplate.js";
+import {
+	ACCESSIBILITY_STATE_REQUIRED,
+	ACCESSIBILITY_STATE_DISABLED,
+	ACCESSIBILITY_STATE_READONLY,
+	LISTITEMCUSTOM_TYPE_TEXT,
+} from "./generated/i18n/i18n-defaults.js";
 
 // Styles
 import ListItemCustomCss from "./generated/themes/ListItemCustom.css.js";
@@ -34,6 +43,8 @@ import ListItemCustomCss from "./generated/themes/ListItemCustom.css.js";
 	styles: [ListItem.styles, ListItemCustomCss],
 })
 class ListItemCustom extends ListItem {
+	@i18n("@ui5/webcomponents")
+	static i18nBundle: I18nBundle;
 	/**
 	 * Defines whether the item is movable.
 	 * @default false
@@ -54,6 +65,12 @@ class ListItemCustom extends ListItem {
 	@property()
 	declare accessibleName?: string;
 
+	/**
+	 * @public
+	 */
+	@slot({ type: Node, "default": true })
+	content!: Array<Node>;
+
 	async _onkeydown(e: KeyboardEvent) {
 		const isTab = isTabNext(e) || isTabPrevious(e);
 		const isFocused = this.matches(":focus");
@@ -76,6 +93,249 @@ class ListItemCustom extends ListItem {
 		super._onkeyup(e);
 	}
 
+	get _accessibleNameRef(): string {
+		if (this.accessibleName) {
+			// accessibleName is set - return labels excluding content
+			return `${this._id}-invisibleText`;
+		}
+
+		// accessibleName is not set - return _accInfo.listItemAriaLabel including custom content announcements
+		return `${this._id}-invisibleTextContent ${this._id}-invisibleText`;
+	}
+
+	_onfocusin(e: FocusEvent) {
+		super._onfocusin(e);
+		this._updateInvisibleTextContent();
+	}
+
+	_onfocusout(e: FocusEvent) {
+		super._onfocusout(e);
+		this._clearInvisibleTextContent();
+	}
+
+	onAfterRendering() {
+		// This will run after the component is rendered
+		if (this.shadowRoot && !this.shadowRoot.querySelector(`#${this._id}-invisibleTextContent`)) {
+			const span = document.createElement("span");
+			span.id = `${this._id}-invisibleTextContent`;
+			span.className = "ui5-hidden-text";
+			// Empty content as requested
+			this.shadowRoot.appendChild(span);
+		}
+	}
+
+	/**
+	 * Returns the invisible text span element used for accessibility announcements
+	 * @returns The invisible text span element or null if not found
+	 * @private
+	 */
+	private get _invisibleTextSpan(): HTMLElement | null {
+		return this.shadowRoot?.querySelector(`#${this._id}-invisibleTextContent`) as HTMLElement;
+	}
+
+	private _updateInvisibleTextContent() {
+		const invisibleTextSpan = this._invisibleTextSpan;
+		if (!invisibleTextSpan) {
+			return;
+		}
+
+		// Get accessibility descriptions
+		const accessibilityTexts = this._getAccessibilityDescription();
+
+		// Create a new array with the type text at the beginning
+		const allTexts = [ListItemCustom.i18nBundle.getText(LISTITEMCUSTOM_TYPE_TEXT), ...accessibilityTexts];
+
+		// Update the span content
+		invisibleTextSpan.textContent = allTexts.join(". ");
+	}
+
+	private _clearInvisibleTextContent() {
+		const invisibleTextSpan = this._invisibleTextSpan;
+		if (invisibleTextSpan) {
+			invisibleTextSpan.textContent = "";
+		}
+	}
+
+	/**
+	 * Gets accessibility description by processing content nodes and delete buttons
+	 * @returns {string[]} Array of accessibility text strings
+	 * @private
+	 */
+	private _getAccessibilityDescription(): string[] {
+		const accessibilityTexts: string[] = [];
+
+		// Process slotted content elements
+		this.content.forEach(child => {
+			this._processNodeForAccessibility(child, accessibilityTexts);
+		});
+
+		// Process delete button in delete mode
+		const deleteButtonNodes = this._getDeleteButtonNodes();
+		deleteButtonNodes.forEach(button => {
+			this._processNodeForAccessibility(button, accessibilityTexts);
+		});
+
+		return accessibilityTexts;
+	}
+
+	/**
+	 * Gets delete button nodes to process for accessibility
+	 * @returns {Node[]} Array of nodes to process
+	 * @private
+	 */
+	private _getDeleteButtonNodes(): Node[] {
+		if (!this.modeDelete) {
+			return [];
+		}
+
+		if (this.hasDeleteButtonSlot) {
+			// Return custom delete buttons from slot
+			return this.deleteButton;
+		}
+
+		// Return the built-in delete button from the shadow DOM if it exists
+		const deleteButton = this.shadowRoot?.querySelector(`#${this._id}-deleteSelectionElement`);
+		return deleteButton ? [deleteButton] : [];
+	}
+
+	/**
+	 * Processes a node and adds its accessible text to the given array
+	 * @param {Node | null} node The node to process
+	 * @param {string[]} textArray The array to add the text to
+	 * @private
+	 */
+	private _processNodeForAccessibility(node: Node | null, textArray: string[]): void {
+		if (!node) {
+			return;
+		}
+
+		const text = this._getElementAccessibleText(node);
+		if (text) {
+			textArray.push(text);
+		}
+	}
+
+	/**
+	 * Extract accessible text from a node and its children recursively.
+	 * UI5 elements provide accessibilityInfo with description and children.
+	 * For elements without accessibilityInfo, we fall back to extracting text content.
+	 *
+	 * @param {Node | null} node The node to extract text from
+	 * @returns {string} The extracted text
+	 * @private
+	 */
+	private _getElementAccessibleText(nodeArg: Node | null): string {
+		if (!nodeArg) {
+			return "";
+		}
+
+		// Handle text nodes directly
+		if (nodeArg.nodeType === Node.TEXT_NODE) {
+			return nodeArg.textContent?.trim() || "";
+		}
+
+		// Only proceed with Element-specific operations for Element nodes
+		if (nodeArg.nodeType !== Node.ELEMENT_NODE) {
+			return "";
+		}
+
+		const element = nodeArg as Element;
+
+		// First, check for accessibilityInfo - expected for all UI5 elements
+		const accessibilityInfo = (element as any).accessibilityInfo as AccessibilityInfo | undefined;
+		if (accessibilityInfo) {
+			return this._processAccessibilityInfo(accessibilityInfo);
+		}
+
+		// Fallback: If no accessibilityInfo is available, extract text content
+		// This applies to standard HTML elements or UI5 elements missing accessibilityInfo
+
+		// 1. Get direct text nodes
+		const textNodeContent = Array.from(element.childNodes || [])
+			.filter(node => node.nodeType === Node.TEXT_NODE)
+			.map(node => node.textContent?.trim())
+			.filter(Boolean)
+			.join(" ");
+
+		// 2. Process shadow DOM if available (for web components)
+		let shadowContent = "";
+		if ((element as HTMLElement).shadowRoot) {
+			shadowContent = Array.from((element as HTMLElement).shadowRoot!.childNodes)
+				.map(childNode => this._getElementAccessibleText(childNode))
+				.filter(Boolean)
+				.join(" ");
+		}
+
+		// 3. Process child elements recursively
+		const childContent = Array.from(element.children || [])
+			.map(child => this._getElementAccessibleText(child))
+			.filter(Boolean)
+			.join(" ");
+
+		// Combine all text sources
+		return [textNodeContent, shadowContent, childContent].filter(Boolean).join(" ");
+	}
+
+	/**
+	 * Process accessibility info from UI5 elements
+	 * @param {AccessibilityInfo} accessibilityInfo The accessibility info object
+	 * @returns {string} Processed accessibility text
+	 * @private
+	 */
+	private _processAccessibilityInfo(accessibilityInfo: AccessibilityInfo): string {
+		// Extract primary information from accessibilityInfo
+		const {
+			type, description, required, disabled, readonly, children,
+		} = accessibilityInfo;
+
+		// Build main text from description (primary) and type
+		const textParts: string[] = [];
+
+		// Description is the primary content for accessibility
+		if (description) {
+			textParts.push(description);
+		}
+
+		// Type is added next
+		if (type) {
+			textParts.push(type);
+		}
+
+		// Add accessibility states
+		const states: string[] = [];
+		if (required) {
+			states.push(ListItemCustom.i18nBundle.getText(ACCESSIBILITY_STATE_REQUIRED));
+		}
+		if (disabled) {
+			states.push(ListItemCustom.i18nBundle.getText(ACCESSIBILITY_STATE_DISABLED));
+		}
+		if (readonly) {
+			states.push(ListItemCustom.i18nBundle.getText(ACCESSIBILITY_STATE_READONLY));
+		}
+
+		// Build text with states
+		let mainText = textParts.join(" ");
+		if (states.length > 0) {
+			mainText = [mainText, states.join(" ")].filter(Boolean).join(" ");
+		}
+
+		// Process accessibility children if provided
+		let childrenText = "";
+		if (children && children.length > 0) {
+			childrenText = children
+				.map(child => this._getElementAccessibleText(child))
+				.filter(Boolean)
+				.join(". ");
+
+			// Combine main text with children text
+			if (childrenText) {
+				return [mainText, childrenText].filter(Boolean).join(". ");
+			}
+		}
+
+		return mainText;
+	}
+
 	get classes(): ClassMap {
 		const result = super.classes;
 
diff --git a/packages/main/src/i18n/messagebundle.properties b/packages/main/src/i18n/messagebundle.properties
index f5779d84beb6..ed88b4fb14cd 100644
--- a/packages/main/src/i18n/messagebundle.properties
+++ b/packages/main/src/i18n/messagebundle.properties
@@ -568,6 +568,9 @@ TOKEN_ARIA_REMOVE=Remove
 #XACT: ARIA announcement for token label
 TOKEN_ARIA_LABEL=Token
 
+#XACT: ARIA announcement for custom list item type
+LISTITEMCUSTOM_TYPE_TEXT=List Item
+
 #XACT: ARIA announcement for tokens
 TOKENIZER_ARIA_CONTAIN_TOKEN=No Tokens
 
@@ -933,3 +936,12 @@ DYNAMIC_DATE_RANGE_NEXT_COMBINED_TEXT=Next X {0} (included)
 
 #XFLD: Suffix text for included date range options.
 DYNAMIC_DATE_RANGE_INCLUDED_TEXT=(included)
+
+#XACT: ARIA announcement for required accessibility state
+ACCESSIBILITY_STATE_REQUIRED=required
+
+#XACT: ARIA announcement for disabled accessibility state
+ACCESSIBILITY_STATE_DISABLED=disabled
+
+#XACT: ARIA announcement for read-only accessibility state
+ACCESSIBILITY_STATE_READONLY=read only