diff --git a/ports/raspberrypi/boards/waveshare_rp2350_usb/board.c b/ports/raspberrypi/boards/waveshare_rp2350_usb/board.c
new file mode 100644
index 0000000000000..7beb58abe285f
--- /dev/null
+++ b/ports/raspberrypi/boards/waveshare_rp2350_usb/board.c
@@ -0,0 +1,17 @@
+// This file is part of the CircuitPython project: https://circuitpython.org
+//
+// SPDX-FileCopyrightText: Copyright (c) 2021 Scott Shawcroft for Adafruit Industries
+//
+// SPDX-License-Identifier: MIT
+
+#include "supervisor/board.h"
+
+#include "shared-bindings/digitalio/DigitalInOut.h"
+#include "shared-bindings/usb_host/Port.h"
+#include "hardware/gpio.h"
+
+// Use the MP_WEAK supervisor/shared/board.c versions of routines not defined here.
+
+void board_init(void) {
+    common_hal_usb_host_port_construct(&pin_GPIO12, &pin_GPIO13);
+}
diff --git a/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.h b/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.h
new file mode 100644
index 0000000000000..f4c53a8aff83e
--- /dev/null
+++ b/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.h
@@ -0,0 +1,15 @@
+// This file is part of the CircuitPython project: https://circuitpython.org
+//
+// SPDX-FileCopyrightText: Copyright (c) 2021 Scott Shawcroft for Adafruit Industries
+// SPDX-FileCopyrightText: Copyright (c) 2024 Cooper Dalrymple
+//
+// SPDX-License-Identifier: MIT
+
+#pragma once
+
+#define MICROPY_HW_BOARD_NAME "Waveshare RP2350-USB-A"
+#define MICROPY_HW_MCU_NAME "rp2350"
+
+#define MICROPY_HW_NEOPIXEL (&pin_GPIO16)
+
+#define CIRCUITPY_USB_HOST_INSTANCE 1
diff --git a/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.mk b/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.mk
new file mode 100644
index 0000000000000..4494b1c3e1f60
--- /dev/null
+++ b/ports/raspberrypi/boards/waveshare_rp2350_usb/mpconfigboard.mk
@@ -0,0 +1,12 @@
+USB_VID = 0x2E8A
+USB_PID = 0x10B1
+USB_PRODUCT = "RP2350-USB-A"
+USB_MANUFACTURER = "Waveshare Electronics"
+
+CHIP_VARIANT = RP2350
+CHIP_PACKAGE = A
+CHIP_FAMILY = rp2
+
+EXTERNAL_FLASH_DEVICES = "W25Q16JVxQ"
+
+CIRCUITPY__EVE = 1
diff --git a/ports/raspberrypi/boards/waveshare_rp2350_usb/pico-sdk-configboard.h b/ports/raspberrypi/boards/waveshare_rp2350_usb/pico-sdk-configboard.h
new file mode 100644
index 0000000000000..110195b779498
--- /dev/null
+++ b/ports/raspberrypi/boards/waveshare_rp2350_usb/pico-sdk-configboard.h
@@ -0,0 +1,9 @@
+// This file is part of the CircuitPython project: https://circuitpython.org
+//
+// SPDX-FileCopyrightText: Copyright (c) 2021 Scott Shawcroft for Adafruit Industries
+//
+// SPDX-License-Identifier: MIT
+
+#pragma once
+
+// Put board-specific pico-sdk definitions here. This file must exist.
diff --git a/ports/raspberrypi/boards/waveshare_rp2350_usb/pins.c b/ports/raspberrypi/boards/waveshare_rp2350_usb/pins.c
new file mode 100644
index 0000000000000..1f80afab9663f
--- /dev/null
+++ b/ports/raspberrypi/boards/waveshare_rp2350_usb/pins.c
@@ -0,0 +1,50 @@
+// This file is part of the CircuitPython project: https://circuitpython.org
+//
+// SPDX-FileCopyrightText: Copyright (c) 2021 Scott Shawcroft for Adafruit Industries
+//
+// SPDX-License-Identifier: MIT
+
+#include "shared-bindings/board/__init__.h"
+
+static const mp_rom_map_elem_t board_module_globals_table[] = {
+    CIRCUITPYTHON_BOARD_DICT_STANDARD_ITEMS
+
+    // 0-10 are wired up to the header
+    { MP_ROM_QSTR(MP_QSTR_GP0), MP_ROM_PTR(&pin_GPIO0) },
+    { MP_ROM_QSTR(MP_QSTR_GP1), MP_ROM_PTR(&pin_GPIO1) },
+    { MP_ROM_QSTR(MP_QSTR_GP2), MP_ROM_PTR(&pin_GPIO2) },
+    { MP_ROM_QSTR(MP_QSTR_GP3), MP_ROM_PTR(&pin_GPIO3) },
+    { MP_ROM_QSTR(MP_QSTR_GP4), MP_ROM_PTR(&pin_GPIO4) },
+    { MP_ROM_QSTR(MP_QSTR_GP5), MP_ROM_PTR(&pin_GPIO5) },
+    { MP_ROM_QSTR(MP_QSTR_GP6), MP_ROM_PTR(&pin_GPIO6) },
+    { MP_ROM_QSTR(MP_QSTR_GP7), MP_ROM_PTR(&pin_GPIO7) },
+    { MP_ROM_QSTR(MP_QSTR_GP8), MP_ROM_PTR(&pin_GPIO8) },
+    { MP_ROM_QSTR(MP_QSTR_GP9), MP_ROM_PTR(&pin_GPIO9) },
+    { MP_ROM_QSTR(MP_QSTR_GP10), MP_ROM_PTR(&pin_GPIO10) },
+
+    // 26-29 are wired to the header, also as analog
+    { MP_ROM_QSTR(MP_QSTR_GP26_A0), MP_ROM_PTR(&pin_GPIO26) },
+    { MP_ROM_QSTR(MP_QSTR_GP26), MP_ROM_PTR(&pin_GPIO26) },
+    { MP_ROM_QSTR(MP_QSTR_A0), MP_ROM_PTR(&pin_GPIO26) },
+
+    { MP_ROM_QSTR(MP_QSTR_GP27_A1), MP_ROM_PTR(&pin_GPIO27) },
+    { MP_ROM_QSTR(MP_QSTR_GP27), MP_ROM_PTR(&pin_GPIO27) },
+    { MP_ROM_QSTR(MP_QSTR_A1), MP_ROM_PTR(&pin_GPIO27) },
+
+    { MP_ROM_QSTR(MP_QSTR_GP28_A2), MP_ROM_PTR(&pin_GPIO28) },
+    { MP_ROM_QSTR(MP_QSTR_GP28), MP_ROM_PTR(&pin_GPIO28) },
+    { MP_ROM_QSTR(MP_QSTR_A2), MP_ROM_PTR(&pin_GPIO28) },
+
+    { MP_ROM_QSTR(MP_QSTR_GP29_A3), MP_ROM_PTR(&pin_GPIO29) },
+    { MP_ROM_QSTR(MP_QSTR_GP29), MP_ROM_PTR(&pin_GPIO29) },
+    { MP_ROM_QSTR(MP_QSTR_A3), MP_ROM_PTR(&pin_GPIO29) },
+
+    // 12 & 13 are pio USB P and N respectively
+    { MP_ROM_QSTR(MP_QSTR_USB_HOST_DATA_PLUS), MP_ROM_PTR(&pin_GPIO12) },
+    { MP_ROM_QSTR(MP_QSTR_USB_HOST_DATA_MINUS), MP_ROM_PTR(&pin_GPIO13) },
+
+    // RGB LED on 16
+    { MP_ROM_QSTR(MP_QSTR_LED), MP_ROM_PTR(&pin_GPIO16) },
+    { MP_ROM_QSTR(MP_QSTR_GP16), MP_ROM_PTR(&pin_GPIO16) },
+};
+MP_DEFINE_CONST_DICT(board_module_globals, board_module_globals_table);