-
Notifications
You must be signed in to change notification settings - Fork 1
Commit
This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository.
Added documentation .tex file. Needs to be built before distributing …
…the package. Updated the README file to reflect this. Implemented in top level Makefile.am.
- Loading branch information
cpjewell
committed
Sep 23, 2014
1 parent
80a2ae6
commit edfec89
Showing
3 changed files
with
108 additions
and
9 deletions.
There are no files selected for viewing
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
|
@@ -8,14 +8,15 @@ The code contained in this repository runs alongside research conducted between | |
The software is distributed under the GPLv3 license, allowing users to modify and redistribute the source code. | ||
It is provided WITHOUT WARRANTY and is intended for academic research purposes. | ||
|
||
Copyright Chris Jewell <[email protected]> 2012 | ||
|
||
Copyright Chris Jewell <[email protected]> 2014 | ||
|
||
See $(PREFIX)/doc/%PACKAGE%/model.pdf for technical model details. | ||
|
||
System requirements | ||
==================== | ||
|
||
Boost >= 1.51.0 with program_options and boost_mpi compiled in. | ||
MPI library compatible with Boost::MPI >= 1.51.0 | ||
Boost >= 1.51.0 with boost_program_options, boost_serialization and boost_mpi compiled in. | ||
GNU Scientific Library >= 1.15 | ||
|
||
Compiling | ||
|
@@ -33,11 +34,12 @@ Non-standard library locations | |
============================== | ||
|
||
To point the build process at non-standard library locations | ||
(e.g. for GSL and Boost), use the CXXFLAGS and LDFLAGS environment | ||
variables. For example: | ||
(e.g. for GSL and Boost), use the --with-gsl-prefix and --with-boost | ||
options to configure. For example: | ||
|
||
$ ./configure --with-gsl-prefix=/usr/local/packages/gsl-1.15 --with-boost=/usr/local/packages/boost_1_51_0 | ||
|
||
$ ./configure CXXFLAGS="-I/usr/local/packages/gsl-1.15/include -I/usr/local/packages/boost_1_51_0/include" \ | ||
LDFLAGS="-L/usr/local/packages/gsl-1.15/lib -L/usr/local/packages/boost_1_51_0/lib" | ||
See ./configure --help for further options for selecting GSL and Boost locations. | ||
|
||
|
||
Running %PACKAGE% | ||
|
@@ -60,6 +62,18 @@ The main configuration is set by using the -c switch. See $(PREFIX)/share/%PACK | |
an example config file which you can edit. Change the values in this file, BUT DO NOT ALTER THE | ||
STRUCTURE OF THE XML. | ||
|
||
The output files are named according to the output file prefix, with .parms and .occ appended. This | ||
version of %PACKAGE% writes nothing to the .occ file, and the posterior draws for the parameters are | ||
contained in the .parms file. The latter is CSV format, with the names of the parameters as column headings. | ||
Each row then contains a sample of the chain for each iteration. | ||
|
||
Since auseiMcmc is built using MPI, you can run it under 'mpirun' for parallel execution. The MCMC | ||
algorithm requires /fast/ interconnects, so it is recommended to either run the package on a large | ||
multicore machine, or on a specialised distributed HPC system. For example: | ||
|
||
$ mpirun -np 128 auseiMcmc -c myConf.xml | ||
|
||
|
||
Population file format | ||
====================== | ||
|
||
|
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Original file line number | Diff line number | Diff line change |
---|---|---|
@@ -0,0 +1,85 @@ | ||
\documentclass[english]{article} | ||
\usepackage[T1]{fontenc} | ||
\usepackage[latin9]{inputenc} | ||
\usepackage{geometry} | ||
\geometry{verbose,tmargin=2cm,bmargin=2cm,lmargin=2cm,rmargin=2cm} | ||
\setlength{\parskip}{\medskipamount} | ||
\setlength{\parindent}{0pt} | ||
\usepackage{bm} | ||
\usepackage{amsmath} | ||
\usepackage{babel} | ||
\begin{document} | ||
|
||
\title{Australian Equine Influenza model} | ||
|
||
\maketitle | ||
|
||
\section{infer-ausei version 4.0} | ||
|
||
The following documentation describes the model used in infer-ausei | ||
version 4.0. Please refer to the \texttt{README} file for details | ||
of how to make inference on this model. | ||
|
||
|
||
\subsection{Between-property model} | ||
|
||
The state of properties during the epidemic is modelled as a continuous | ||
time SIO (Susceptible, Infected, Onset) process, with pairwise transmission | ||
rate | ||
\[ | ||
\beta_{ij}(t)=\mu\cdot h_{i}(t-I_{i})n_{i}a_{i}^{\xi}\cdot n_{j}a_{j}^{\zeta}\theta^{\bm{1}[j\in\mathcal{V}(t)]}\frac{\delta}{\delta^{2}+\rho_{ij}^{2}}\hspace{1em}i\in\mathcal{I},j\in\mathcal{S} | ||
\] | ||
and assumes a fixed 2 day time from infection to onset \emph{at the | ||
between property level}. $\mu$ is the baseline transmission rate, | ||
$n_{k}$ is the number of horses on property $k$, $a_{k}$ is the | ||
area of property $k$ with non-linear parameters $\xi$ and $\zeta$ | ||
giving the effect (note that if these non-linear parameters were 0, | ||
this would imply no effect of area). $\theta$ is the effect of vaccination | ||
on the susceptible properties with $\mathcal{V}(t)$ the set of vaccinated | ||
properties at time $t$. $\rho_{ij}$ is the Euclidean distances (map-units/1000) | ||
between centroids(?) of the properties $i$ and $j$, and $\delta$ | ||
is the decay parameter for our Cauchy distance kernel. The function | ||
$h_{i}(t-I_{i})$ is the infectivity of property $i$, taken to be | ||
proportional to the number of animals infected according to the within-property | ||
model described below. | ||
|
||
At time $t$, the \emph{infectious pressure} $\lambda_{j}(t)$ on | ||
property $j$ is | ||
\[ | ||
\lambda_{j}(t)=\epsilon_{t}+\sum_{i\in}\beta_{ij}(t) | ||
\] | ||
where | ||
\[ | ||
\epsilon_{t}=\begin{cases} | ||
\epsilon_{0} & \mbox{ if }t<10\\ | ||
\epsilon_{10} & \mbox{if }10\leq t<44\\ | ||
\epsilon_{44} & \mbox{if }44\leq t | ||
\end{cases} | ||
\] | ||
corresponding to control events at $t=10$ and $t=44$ (remind me | ||
what these events were?). | ||
|
||
|
||
\subsection{Within-property model} | ||
|
||
At the \emph{within property level}, $h_{i}(s)=I_{i}(s)/n_{i}$ function | ||
returns the proportion of horses infected on property $i$ at time | ||
$s$ after $i$'s infection time, where $I_{i}(s)$ is the solution | ||
to a deterministic SEIR model | ||
|
||
\begin{eqnarray*} | ||
\frac{dS_{i}(t)}{dt} & = & -\beta\frac{S_{i}(t)I_{i}(t)}{n_{i}}\\ | ||
\frac{dE_{i}(t)}{dt} & = & \beta\frac{S_{i}(t)I_{i}(t)}{n_{i}}-\omega E_{i}(t)\\ | ||
\frac{dI_{i}(t)}{dt} & = & \omega E_{i}(t)-\nu I_{i}(t)\\ | ||
\frac{dR_{i}(t)}{dt} & = & \nu I_{i}(t) | ||
\end{eqnarray*} | ||
|
||
|
||
where $\omega=$1 and $\nu=1/6$. We set $h(s)$=0 for $I_{i}(s)<0.5$ | ||
horses. | ||
|
||
Note that a property ``runs out'' of infectiousness as all the horses | ||
recover. This is why the SIO model above does not have an ``R'' | ||
compartment -- ``O'' stage properties simply stop being infectious | ||
after a while. | ||
\end{document} |