diff --git a/pandas/core/col.py b/pandas/core/col.py
index 39c4a7fd016c2..814b714bdbe2f 100644
--- a/pandas/core/col.py
+++ b/pandas/core/col.py
@@ -37,6 +37,8 @@
     "__lt__": "<",
     "__eq__": "==",
     "__ne__": "!=",
+    "__and__": "&",
+    "__rand__": "&",
 }
 
 
@@ -157,6 +159,12 @@ def __mod__(self, other: Any) -> Expression:
     def __rmod__(self, other: Any) -> Expression:
         return self._with_binary_op("__rmod__", other)
 
+    def __and__(self, other: Any) -> Expression:
+        return self._with_binary_op("__and__", other)
+
+    def __rand__(self, other: Any) -> Expression:
+        return self._with_binary_op("__rand__", other)
+
     def __array_ufunc__(
         self, ufunc: Callable[..., Any], method: str, *inputs: Any, **kwargs: Any
     ) -> Expression:
diff --git a/pandas/tests/test_col.py b/pandas/tests/test_col.py
index c884540abfed0..6883532432465 100644
--- a/pandas/tests/test_col.py
+++ b/pandas/tests/test_col.py
@@ -46,6 +46,36 @@ def test_col_simple(
     assert str(expr) == expected_str
 
 
+@pytest.mark.parametrize(
+    ("expr", "expected_values", "expected_str"),
+    [
+        (
+            (pd.col("a") >= 3) & (pd.col("a") <= 5),
+            [3, 4, 5],
+            "((col('a') >= 3) & (col('a') <= 5))",
+        ),
+        (
+            (pd.col("b") >= 20) & (pd.col("a") <= 5),
+            [1, 2, 3],
+            "((col('b') >= 20) & (col('a') <= 5))",
+        ),
+        (
+            (pd.col("b") >= 20) & (pd.col("a") <= 5) & (pd.col("b") < 22),
+            [2, 3],
+            "(((col('b') >= 20) & (col('a') <= 5)) & (col('b') < 22))",
+        ),
+    ],
+)
+def test_col_bool(
+    expr: Expression, expected_values: list[object], expected_str: str
+) -> None:
+    df = pd.DataFrame({"a": list(range(1, 21)), "b": list(range(22, 2, -1))})
+    result = df.loc[expr]
+    ls = result["a"].tolist()
+    assert ls == expected_values
+    assert str(expr) == expected_str
+
+
 @pytest.mark.parametrize(
     ("expr", "expected_values", "expected_str"),
     [