diff --git a/.github/workflows/dnmtools_build_macos.yml b/.github/workflows/dnmtools_build_macos.yml
index a75541cf..2adda8fc 100644
--- a/.github/workflows/dnmtools_build_macos.yml
+++ b/.github/workflows/dnmtools_build_macos.yml
@@ -8,7 +8,7 @@ on:
     branches: [ "master" ]
 
 jobs:
-  build-on-x86:
+  build-with-gcc-on-x86:
     runs-on: macos-13
     steps:
     - uses: actions/checkout@v4
@@ -26,7 +26,7 @@ jobs:
       run: ./configure CXX="g++-14" CPPFLAGS="-I$(brew --prefix)/include" LDFLAGS="-L$(brew --prefix)/lib"
     - name: make
       run: make -j4
-  build-on-arm64:
+  build-with-gcc-on-arm64:
     runs-on: macos-15
     steps:
     - uses: actions/checkout@v4
@@ -44,3 +44,21 @@ jobs:
       run: ./configure CXX="g++-14" CPPFLAGS="-I$(brew --prefix)/include" LDFLAGS="-L$(brew --prefix)/lib"
     - name: make
       run: make -j4
+  build-with-clang-on-arm64:
+    runs-on: macos-15
+    steps:
+    - uses: actions/checkout@v4
+      with:
+        submodules: recursive
+    - name: Update Homebrew
+      run: brew update
+    - name: Install autotools
+      run: brew install automake
+    - name: Install dependencies
+      run: brew install htslib gsl
+    - name: Generate configure script
+      run: ./autogen.sh
+    - name: configure with clang++
+      run: ./configure CXX="clang++" CPPFLAGS="-I$(brew --prefix)/include" LDFLAGS="-L$(brew --prefix)/lib"
+    - name: make
+      run: make -j4