diff --git a/crates/swc_ecma_minifier/src/compress/optimize/ops.rs b/crates/swc_ecma_minifier/src/compress/optimize/ops.rs
index 69d0a1b05e27..f8cd64e343e7 100644
--- a/crates/swc_ecma_minifier/src/compress/optimize/ops.rs
+++ b/crates/swc_ecma_minifier/src/compress/optimize/ops.rs
@@ -42,7 +42,10 @@ impl Optimizer<'_> {
         }
 
         if e.op == op!("===") || e.op == op!("!==") {
-            if (e.left.is_ident() || e.left.is_member()) && e.left.eq_ignore_span(&e.right) {
+            if (e.left.is_ident() || e.left.is_member())
+                && e.left.eq_ignore_span(&e.right)
+                && !contains_update_or_assign(&e.left)
+            {
                 self.changed = true;
                 report_change!("Reducing comparison of same variable ({})", e.op);
 
@@ -288,3 +291,71 @@ impl Optimizer<'_> {
         }
     }
 }
+
+/// Check if an expression contains update expressions (++, --) or assignments
+/// that would make duplicate evaluations produce different results.
+fn contains_update_or_assign(expr: &Expr) -> bool {
+    match expr {
+        Expr::Update(..) | Expr::Assign(..) => true,
+
+        Expr::Bin(BinExpr { left, right, .. }) => {
+            contains_update_or_assign(left) || contains_update_or_assign(right)
+        }
+
+        Expr::Unary(UnaryExpr { arg, .. }) => contains_update_or_assign(arg),
+
+        Expr::Cond(CondExpr {
+            test, cons, alt, ..
+        }) => {
+            contains_update_or_assign(test)
+                || contains_update_or_assign(cons)
+                || contains_update_or_assign(alt)
+        }
+
+        Expr::Member(MemberExpr { obj, prop, .. }) => {
+            contains_update_or_assign(obj)
+                || match prop {
+                    MemberProp::Computed(ComputedPropName { expr, .. }) => {
+                        contains_update_or_assign(expr)
+                    }
+                    _ => false,
+                }
+        }
+
+        Expr::Call(CallExpr {
+            callee: Callee::Expr(callee),
+            args,
+            ..
+        }) => {
+            contains_update_or_assign(callee)
+                || args.iter().any(|arg| contains_update_or_assign(&arg.expr))
+        }
+
+        Expr::Seq(SeqExpr { exprs, .. }) => {
+            exprs.iter().any(|expr| contains_update_or_assign(expr))
+        }
+
+        Expr::Paren(ParenExpr { expr, .. }) => contains_update_or_assign(expr),
+
+        Expr::OptChain(OptChainExpr { base, .. }) => match &**base {
+            OptChainBase::Member(member) => {
+                contains_update_or_assign(&member.obj)
+                    || match &member.prop {
+                        MemberProp::Computed(ComputedPropName { expr, .. }) => {
+                            contains_update_or_assign(expr)
+                        }
+                        _ => false,
+                    }
+            }
+            OptChainBase::Call(call) => {
+                contains_update_or_assign(&call.callee)
+                    || call
+                        .args
+                        .iter()
+                        .any(|arg| contains_update_or_assign(&arg.expr))
+            }
+        },
+
+        _ => false,
+    }
+}
diff --git a/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/config.json b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/config.json
new file mode 100644
index 000000000000..f48cfc8fc3d6
--- /dev/null
+++ b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/config.json
@@ -0,0 +1,3 @@
+{
+    "comparisons": true
+}
diff --git a/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/input.js b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/input.js
new file mode 100644
index 000000000000..93881315671a
--- /dev/null
+++ b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/input.js
@@ -0,0 +1,5 @@
+// Issue #11255: compress.comparisons should not optimize comparisons with side effects
+let PC = 0;
+const Stack = [0, ''];
+const Code = [0, 0, 1];
+console.log(Stack[Code[++PC]] === Stack[Code[++PC]]);
diff --git a/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.js b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.js
new file mode 100644
index 000000000000..93881315671a
--- /dev/null
+++ b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.js
@@ -0,0 +1,5 @@
+// Issue #11255: compress.comparisons should not optimize comparisons with side effects
+let PC = 0;
+const Stack = [0, ''];
+const Code = [0, 0, 1];
+console.log(Stack[Code[++PC]] === Stack[Code[++PC]]);
diff --git a/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.mangleOnly.js b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.mangleOnly.js
new file mode 100644
index 000000000000..1ab999809dd1
--- /dev/null
+++ b/crates/swc_ecma_minifier/tests/terser/compress/comparing/issue_11255_side_effects/output.mangleOnly.js
@@ -0,0 +1,12 @@
+// Issue #11255: compress.comparisons should not optimize comparisons with side effects
+let o = 0;
+const c = [
+    0,
+    ''
+];
+const l = [
+    0,
+    0,
+    1
+];
+console.log(c[l[++o]] === c[l[++o]]);