About

• Uses gene annotation files (.csv/.xlsx) to generate Distance to Transcription Start Site (TSS) plots.
• Plots represent Distance (in kb) versus the Number of Peaks/Sites at a specific distance.
• Specifically useful for profiling the Distance to TSS profiles for annotated ChIP-Seq, ATAC-Seq, HiC peaks.

Pre-Requisites

Install python modules: pandas,matplotlib,argparse,numpy.

pip install pandas matplotlib argparse numpy

Input annotation file must contain a Distance to TSS column that can be read and interpreted by the tool.

Example: Use annotation files generated by HOMER

Usage

python dist_TSS.py [-h] [--bin_width BIN_WIDTH] [--color COLOR]
                   [--file_format {pdf,png}]
                   input_file output_file